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Cell and Molecular Biology

Dr. M. Balasubramanyam

 
 
Publications  
 
1. Srinivasan V, Sandhya N, Sampathkumar R, Farooq S, Mohan V & Balasubramanyam, M. Glutamine Fructose-6-phosphate amidotransferase (GFAT) gene expression and activity in patients with Type 2 diabetes: inter-relationships with hyperglycemia and oxidative stress. Clinical Biochemistry 2007 (in press).
2. Anitha B, Sampathkumar R, Balasubramanyam M & Rema M. Advanced glycation index and its association with severity of diabetic retinopathy in type 2 diabetic subjects. J. Diabetes and its Complications. 2007 (in press).
3. Balasubramanyam M, Mohan, V. Diabetes in 2007 – What are the promises & challenges? Indian Journal of Medical Res. 125:195-199, 2007.
4. Balasubramanyam M, Adaikalakoteswari, A, Finnymonickaraj, S. Mohan, V. Telomere shortening and metabolic/vascular diseases. Indian Journal of Medical Res. 125: 441-450, 2007.
5.
    Sundarajan S, Srinivasan, V, Balasubramanyam M, Tatu, U. Endoplasmic reticulum (ER) stress and diabetes. Indian Journal of Medical Research. 125: 411-424, 2007.
6. Adaikalakoteswari A, Rema, M, Mohan, V. and M. Balasubramanyam. Oxidative DNA damage and augmentation of Poly (ADP-ribose) polymerase/Nuclear Factor-kappa B signaling in patients with Type 2 diabetes and microangiopathy. International Journal of Biochemistry and Cell Biology (in press).
7. Adaikalakoteswari A, M. Balasubramanyam, M, Ravikumar, R, Deepa. R. and Mohan, V. Association of telomere shortening with impaired glucose tolerance and diabetic macroangiopathy. Atherosclerosis (in press)
8. Sameer, M, Balasubramanyam, M. And Mohan, V. Stem cells and diabetes. Current Science, 91(9):1158-1165, 2006
9. Balasubramanyam, M, Adaikalakoteswari A, Sampathkumar, R and V. Mohan. Oxidative stress in Asian Indians with Type 2 diabetes. In: Type 2 diabetes in South Asians: Epidemiology, Risk Factors and Prevention. Jaypee Brothers, Medical Publishers (P) Ltd., New Delhi, pp 164-172, 2006.
10. Adaikalakoteswari A, M. Balasubramanyam, M. Rema and V. Mohan. Differential gene expression of NADPH oxidase (p22phox) and hemoxygenase-1 in patients with type 2 diabetes and microangiopathy. Diabetic Medicine 23:666-674, 2006.
11. Balasubramanyam M. Antioxidants and cardiovascular disease- Where do we stand? The Asian Journal of Diabetology, 8(1): 1-5, 2006
12. Premanand C, Rema M, Sameer Mahmood Z, Sujatha M, Balasubramanyam M. Effect of curcumin on proliferation of human retinal endothelial cells under invitro conditions. Invest Ophthalmol Vis Sci. 47:2179–2184, 2006.
13. Sampathkumar R, Balasubramanaym M, C.Tara, M.Rema, V.Mohan. Association of hypoglutathionemia with reduced Na+/K+ ATPase activity in type 2 diabetes and microangiopathy. Mol. Cell. Biochem, 282 (1-2):169-76, 2006.
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14. Sampathkumar R, Balasubramanyam M, Sudarslal S, Rema M, Mohan V and Balaram P. Increased glutathionylated hemoglobin (HbSSG) in type 2 diabetes subjects with microangiopathy. Clinical Biochemistry, 38(10):892-9, 2005.
15. Adaikalakoteswari A, Balasubramanyam M and Mohan V. Telomere shortening in patients with Type 2 diabetes. Diabetic Medicine, 22, 1151–1156, 2005.
16. Balasubramanyam M, Sampathkumar R and Mohan V. (2005) Is insulin signaling molecules misguided in diabetes for ubiquitin-proteasome degradation? Mol. Cell. Biochem, 275: 117–125, 2005.
17. Balasubramanyam M Transforming ‘traditional anecdotes’ to ‘evidence-based medicine’ and its relation to diabetes. Current Science, 89(3); 428, 2005
18. Mohan V, Balasubramanyam M, Radha V. Genomics and Proteomics of Type 2 Diabetes in Indians. J Assoc Physicians India, 53: 505-509, 2005.
19. Sampathkumar R, Balasubramayam M, Rema M, et al. A novel advanced glycation index (AGI) and its association with diabetes and microangiopathy. Metabolism, 58: 1004-1007, 2005.
20. Balasubramanyam M, Adaikalakoteswari A & Mohan V. Telomere shortening: A marker of atherosclerosis? Current Science, 87, 422-24, 2004.
21. Balasubramanyam M and Mohan V. (2004) Insulin signaling in Diabetes: Cascades and Complexities. Advanced Biotech. 2: 24-27, 2004.
22. Balasubramanyam M, Adaikalakoteswari A, Sampathkumar R et al. Curcumin-induced inhibition of cellular Reactive Oxygen Species (ROS) generation: Novel therapeutic implications. J. Biosci, 28: 715-721, 2003.
23. BrijendraKumar S, Balasubramanyam M & Mohan V. Scientific highlights of the MDRF-ADA post-graduate course in Diabetology. Int J Diab Dev Countries, 23:135-144, 2003.
24. Balasubramanyam M, Rema M & Premanand C. Biochemical and Molecular Mechanisms of Diabetic retinopathy. Current Science, 83: 1506 -14, 2002.
25. Balasubramanyam M, Premanand C & Mohan V. Lymphocytes as a cellular model to study insights into the pathophysiology of diabetes and its complications.  ANYAS - Annals of New York Academy of Sciences, 958:399-402, 2002.
26. Balasubramanyam M & Mohan V. The need for high throughput screening of herbal medicine with special reference to diabetes mellitus.  In: Biodiversity (monitoring, management, conservation and enhancement) Ramamurthy, R. & Bali, G (Eds), pp. 57-74, 2002.
27. Balasubramanyam M & Mohan V. Orally active insulin mimics: where do we stand now?  J. Biosciences, 26:383-390, 2001.
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28. Mohan, V & Balasubramanyam, M, (2001) Fenugreek and insulin resistance. J. Assoc. Phys. India, 49: 1055-6. 
29. Balasubramanyam M, Balaji RA, Subashini B & Mohan V. Evidence for mechanistic alterations of Ca2+ homeostasis in Type 2 diabetes mellitus. Int. J. Experimental Diab Res, 1: 275-287, 2001.
30. Balasubramanyam M & Mohan V. Current concepts of PPAR-g signaling in Diabetes mellitus. Current Science, 79:1440-1446, 2000.
31. Balasubramanyam M & Mohan V. Signal transduction during cardiac hypertrophy: New insights. Indian Heart J, 52:226-232, 2000.
32. Balasubramanyam M, Miranda P & Mohan V. Carbohydrate metabolism and diabetes: Links to etiology of diabetic complications and therapy. VI Volume of "The Trends in Carbohydrate Chemistry" , 2000.
33. Balasubramanyam M. Calcium and Signal transduction. Indian Journal of Experimental Biology, 35:1138-1139, 1997.
34. Cho JH, Balasubramanyam M, Chernaya G, Gardner et al. Oligomycin inhibits store-dependent calcium influx in chinese hamster ovary cells and Jurkat T-cells. Biochemical Journal, 324:971-980, 1997.
35. Gardner JP, Balasubramanyam M & Studzinski GP. Up-regulation of Ca2+ influx mediated by store-operated channels in HL60 cells induced to differentiate by 1, 25-dihydroxy-vitamin D3. Journal of Cellular Physiology, 172:284-295, 1997.
36. Gardner JP & Balasubramanyam M. Na+/Ca2+ exchange in circulating blood cells. Annals of New York Academy of Sciences, 779:502-514, 1996.
37. Dang AM, Balasubramanyam M, Zenaida Garcia, Raveche ES & Gardner JP. Altered signal transduction in B-1 malignant clones. Immunology and Cell Biology, 73:511-520, 1995.
38. Balasubramanyam M & Gardner JP. Protein kinase C modulates cytosolic free calcium by stimulating calcium pump activity in Jurkat T cells.  Cell Calcium, 18:526-541, 1995.
39. Balasubramanyam M, Rohowsky-Cochan C, Reeves JP and Gardner JP. Na+/Ca2+ exchange-mediated calcium entry in human peripheral blood lymphocytes. Journal of Clinical Investigation, 94:2002-2008, 1994.
40. Balasubramanyam M, Kimura M, Aviv A & Gardner, JP. Kinetics of calcium transport across the lymphocyte plasma membrane.  American Journal of Physiology, 265:C321-C327, 1993.
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